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According to the traditional Korean medicine, Dampness-heat (DH) is an abnormal state of the body that results in a pathological accumulation of dampness and heat. DH is caused by overeating fatty, sweet foods or overdrinking alcohol. Exposure to hot and humid atmospheres is another cause of DH. Although many experimental animal model on various diseases related with DH syndrome were established, DH syndrome dermatitis model is not established. Thus, we introduce the experimental animal model of the dermatitis with DH syndrome. Keywords Dampness-heat syndrome, traditional Korean medicine, experimental animal model, dermatitis Dampness-heat (DH) in traditional Korean medicine (TKM) 外感DH ( 濕熱 ) is a concept in TKM that refers to an abnormal state of the body that results in a pathological accumulation of dampness ( 濕邪 ) and heat ( 熱邪 ). The DH pattern/syndrome is a pattern/syndrome caused by a combination of dampness and heat, either of external or of internal origin, with different manifestations according to location, e.g., jaundice (Song, 2008) when the DH accumulates in the liver and gallbladder, leucorrhea (Im, 2005) various diseases related with DH syndrome. DH model is set up when the DH pours down, and diarrhea (Choi, 2007) for the DH in the intestines, atopic dermatitis for the DH on the skin (Kim, 2006), obesity (Lee, 1996) for the DH all over the body. |
