Post Transplant Human Cytomegalovirus Infection Can Provoke Acute Kidney Allograft Rejection

Autor: Sumit Ranjan Das, Arpita Ghosh, Nasifa Hasan, Sudip Kumar Roy, Sushmita Jha
Rok vydání: 2013
Předmět:
Zdroj: IOSR Journal of Pharmacy and Biological Sciences. 7:66-69
ISSN: 2278-3008
2319-7676
DOI: 10.9790/3008-0736669
Popis: Human Cytomegalovirus (HCMV) infection can trigger immunological cascades leading to kidney allograft rejection. In this study we have selected 17 post renal transplant patients with negative Luminex Donor Specific Antibody (DSA) crossmatch and Complement Dependent Cytotoxicity (CDC) crossmatch with Anti Human Globulin (AHG) augmentation. All the 17 patients were detected with post transplant HCMV infection. 4 of the 17 patients were recognized with rejection symptoms identified histologically and among them 1 patient died. The patient who died was co- infected with blood stream Staphylococcus aureus.
Databáze: OpenAIRE