Popis: |
Atherosclerosis, the cause of coronary artery disease (CAD) and stroke, is in reality not one disease but many different diseases, each with a similar endpoint (vascular lesions) but differing in genetic and environmental contributions. In genetic terms, atherosclerosis is very “heterogeneous.” Within particular populations, genetic differences appear to be of primary importance in determining who will develop atherosclerosis, and its consequent clinical sequelae, and who will not. Between populations, particularly between those populations consuming different levels of dietary fat, environmental influences predominate. |