Etiopathogenesis of oral submucous fibrosis

Autor:	Hardik Mehta, A. V. Ratheesh, GP Sujatha, Brajesh Kumar, Shiva Prasad Shankarmurthy, Ashok
Rok vydání:	2015
Předmět:	Pathology medicine.medical_specialty biology business.industry digestive oral and skin physiology Disease biology.organism_classification medicine.disease Pathogenesis Oral submucous fibrosis Fibrosis Immunology medicine Genetic predisposition Etiology business Gutka Areca
Zdroj:	Journal of Medicine, Radiology, Pathology and Surgery. 1:16-21
ISSN:	2395-2075
DOI:	10.15713/ins.jmrps.40
Popis:	Etiopathogenesis of oral submucous fibrosis (OSF) is been studied for long time and still a fully satisfactory explanation is not obtained. Areca nut is the main etiological factor which is consumed as pan masala, gutka, mawa, and betel quid. It will interfere with the collegen synthesis and degradation causing the fibrosis. Several other etiological agents such as chilli and nutritional deficiency have been studied. Furthermore, the genetic susceptibility and autoimmune nature of disease have been postulated by some others. Current evidence also implicates collagen-related genes in the susceptibility and pathogenesis of OSF.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c063c65022cfc4858b4b52f6e127fcc1 https://doi.org/10.15713/ins.jmrps.40 Zobrazit plný text záznamu