Effects of Common Inorganic Salts on Glycine Polymorphic Transformation: An Insight into Salt-Dependent Polymorphic Selectivity
| Autor: | Guangjun Han, Pui Shan Chow, Reginald B. H. Tan |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
chemistry.chemical_classification
Inorganic chemistry Nucleation Salt (chemistry) 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences 0104 chemical sciences Divalent law.invention Inorganic salts Transformation (genetics) chemistry law Glycine General Materials Science Crystallization 0210 nano-technology Selectivity |
| Zdroj: | Crystal Growth & Design. 16:6499-6505 |
| ISSN: | 1528-7505 1528-7483 |
| Popis: | The effects of typical inorganic salts on solution-mediated polymorphic transformation from metastable α-glycine to stable γ-glycine were investigated, with the measurement of induction times of γ-glycine nucleation being the key objective. Interestingly, it was observed that all the inorganic salts examined in this study considerably shorten induction time, showing that they accelerate γ-glycine secondary nucleation to a great extent. Surprisingly, it was found that the divalent cation salts (Ca(NO3)2 and MgSO4) exert a peculiar effect in that they greatly promote γ-glycine secondary nucleation despite their significant inhibition to γ-glycine growth. Furthermore, it was revealed that the monovalent cation salts (NaCl, KNO3, and (NH4)2SO4) enhance γ-glycine nucleation far more than the divalent cation salts. These obtained results provide an insight into the general observation that the polymorphic selectivity of glycine from unseeded solution crystallization is salt-dependent. All the experimental obser... |
| Databáze: | OpenAIRE |
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