Flavanol of Limonium bicolor

Autor: Guo-lin Zou, Lian-ru Zhang
Rok vydání: 2004
Předmět:
Zdroj: Chemistry of Natural Compounds. 40:602-603
ISSN: 1573-8388
0009-3130
Popis: Plants of the Limonium bicolor (Plumbaginaceae) genus are rich sources of flavonoids [1, 2]. Many of them are used in folk and modern medicine [3–6]. The aerial part of Limonium bicolor Kunze (Bge.) can be used as traditional medicine to enrich the blood and hemostasis, to cure emmeniopathy, as well as to treat carcinoma uteri. [3]. The plant material for this study was collected on the north of China, in August 2000 (Inner Mongulia region, PRC). The air-dried powder was defatted with n-hexane and successively extracted with CHCl3, CHCl3MeOH (9:1) and MeOH in a soxhlet apparatus, each solvent for 6 h, respectively. The methanolic residue was concentrated and chromatographed on Sephadex LH-20, eluted with MeOH; 41 fractions were collected; each fraction was condensed, then submitted to semipreparative HPLC on a Eclipse XDB C18 column (250 × 9.4mm) eluted with a gradient of MeOH-H2O from 5:95 to 60:40 for 55 min (flow rate 1.0 ml/min), which led to the isolation of compounds 1-3. The compounds were identified by UV, mass, and NMR spectra and comparison with authentic samples.
Databáze: OpenAIRE