| Popis: |
2,5-Diarylthiophene-1-oxides have been prepared from readily available arylacetylene precursors via zirconacyclopentadiene intermediates. The isolated yields of the desired thiophene-1-oxides are comparable to those obtained from the oxidation of thiophene derivatives while avoiding the formation of over-oxidation products. Furthermore, this route offers broader versatility than commonly used methods by providing products outfitted with electron-donating or electron-withdrawing groups with very little variation in isolated product yields. Finally, this strategy provides access to products containing functional groups that are not compatible with oxidation conditions. |
Plný text