| Popis: |
Introduction Despite recommendations for universal screening and intrapartum antibiotic prophylaxis strategies for pregnant women, group B Streptococcus (GBS) remains a major cause of neonatal disease. The aim of our study was to determine the incidence, risk factors and outcome of maternal-fetal infection (MFI) due to GBS. Methods A retrospective study of all cases of neonatal streptococcal B infections arising within 72 hours of birth between January 2012 and December 2017 in our department. Results Eighty-eight cases were indentified which represents 9.6‰ of total hospitalizations during the study period. The sex ratio was 1,4. Fifty four percent (n=48) of cases were associated to bacteraemia and only 2 cases of meningitis were noted. Infectious risk factors were acute fetal hypoxia (42%), peripartum maternal fever (35,2%) and membrane rupture more than 12 hours before delivery (26,1%). Sixteen percent of all newborns were premature and 19,3% had a low birth weight. 64.8% were symptomatic at birth. The main clinical signs were respiratory distress (82.5%), neurologic distress (17.5%) and fever (12.3%). Assisted ventilation was required in 11 patients, 5 of whom died. Predictive factors for bad prognosis were prematurity (2case), severe hypoxemia (2case), nosocomial infections (1case). Conclusions We noted a decrease in the mortality rate, due to advances in the neonatal care. However, neonatal streptococcal B infections still remain a significant problem of public health requiring additional preventive and therapeutic management based on systematic screening and antibiotic prophylaxis. |
