| Autor: |
Audrey S. Baur, Christiane Meugé-Moraw, V. Parlier, Martine Jotterand, P.M. Schmidt, Françoise Delacrétaz |
| Rok vydání: |
2000 |
| Předmět: |
|
| Zdroj: |
European Journal of Haematology. 64:71-79 |
| ISSN: |
0902-4441 |
| DOI: |
10.1034/j.1600-0609.2000.90047.x |
| Popis: |
CD34/QBEND10 immunostaining has been assessed in 150 bone marrow biopsies (BMB) including 91 myelodysplastic syndromes (MDS), 16 MDS-related AML, 25 reactive BMB, and 18 cases where RA could neither be established nor ruled out. All cases were reviewed and classified according to the clinical and morphological FAB criteria. The percentage of CD34-positive (CD34 +) hematopoietic cells and the number of clusters of CD34+ cells in 10 HPF were determined. In most cases the CD34+ cell count was similar to the blast percentage determined morphologically. In RA, however, not only typical blasts but also less immature hemopoietic cells lying morphologically between blasts and promyelocytes were stained with CD34. The CD34+ cell count and cluster values were significantly higher in RA than in BMB with reactive changes (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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