1,2-Dimethoxyvinyllithium–A Useful New Reagent

Autor:	Carl N. Skold
Rok vydání:	1976
Předmět:	chemistry.chemical_classification Chemistry Reagent Organic Chemistry Methoxyacetaldehyde Organic chemistry Aldol condensation Aldehyde
Zdroj:	Synthetic Communications. 6:119-124
ISSN:	1532-2432 0039-7911
DOI:	10.1080/00397917608072620
Popis:	In our work on the synthesis of cephalotaxine, we wished to prepare the α-methoxy-αβ-unsaturated aldehyde 2. Since aldehyde 1 was available2, we needed to find an efficient method for carrying what is effectively an aldol condensation between aldehyde 1 and methoxyacetaldehyde. There are relatively few methods reported in the literature for effecting this transformation.3 We wish to report that the reaction of aldehydes and ketones with 1,2-dimethoxyvinyllithium, followed by acidic rearrangement of the result
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bffd13c0c090f8f3c7824e4a8d1c11e2 https://doi.org/10.1080/00397917608072620 Zobrazit plný text záznamu