Impact of Craniocerebral Hypothermia and Cryopreserved Cord Blood on Reproductive Function of Male Rats with Chronic Alcohol Intoxication
| Autor: | Olga V. Kudokotseva, Vladyslav Babiichuk, Yevhenii Kryshtal, Іvan Lomakin |
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| Rok vydání: | 2020 |
| Předmět: |
Reproductive function
business.industry Biophysics Medicine (miscellaneous) Physiology Hypothermia Chronic alcohol Cryopreservation 03 medical and health sciences 0302 clinical medicine Cord blood Male rats medicine 030212 general & internal medicine medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Problems of Cryobiology and Cryomedicine. 30:369-379 |
| ISSN: | 2518-7376 2307-6143 |
| DOI: | 10.15407/cryo30.04.369 |
| Popis: | In this work, we have studied the impact of chronic alcohol intoxication (CAI) on reproductive function in male rats. Prolonged alcohol abuse has been shown to significantly reduce the manifestation rate of sexual activation and testosterone level in blood serum of male rats with CAI following exposure to a receptive female, as well as to change their seminal fl uid composition. The rhythmic craniocerebral hypothermia (rCCH), combined with the administration of cryopreserved cord blood leukoconcentrate (cCBL) ensured to a greater extent the dynamics of functional integrity recovery of the CAI-altered reproductive system in male rats, if compared to each of these methods used solely. The authors have hypothesized the rCCH and cCBL to activate the hypothalamicpituitary system, affecting thereby the testosterone synthesis and spermatogenesis stimulation. |
| Databáze: | OpenAIRE |
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