IN VITRO ANTI- INFLAMMATORY STUDIES ON SILVER NANOPARTICLES SYNTHESIZED FROM CENTRATHERUM PUNCTATUM CASS
| Autor: | Arun K P, Brindha P, Balaji K, Niraimathi K L, Krithika S, Narendran R |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Aqueous solution
biology medicine.drug_class Chemistry DPPH Pharmaceutical Science 02 engineering and technology 021001 nanoscience & nanotechnology biology.organism_classification Anti-inflammatory In vitro Centratherum Silver nanoparticle 03 medical and health sciences chemistry.chemical_compound Silver nitrate 0302 clinical medicine Phytochemical 030220 oncology & carcinogenesis Drug Discovery medicine Organic chemistry 0210 nano-technology |
| Zdroj: | International Journal of Research in Ayurveda & Pharmacy. 7:61-66 |
| ISSN: | 2277-4343 |
| DOI: | 10.7897/2277-4343.07258 |
| Popis: | This paper presents an empirical analysis on the use of aqueous extract of Centratherum punctatum Cass (Astera ceae) for the production of silver nanoparticles (AgNPs) from aqueous silver nitrate. Phytochemical analysis of the extract reve aled the presence of essential components such as flavonoids, alkaloids, carbohydrates, tannins and vitamin C, some of which serve as efficient reducing and capping agents for the reduction of silver nitrate to silver nanoparticles. The AgNPs synthesized w ere characterized by UV - Vis spectroscopy, FT - IR, XPS, SEM, TEM, Zetasizer and TG - DSC analyzer. In the present study , attempts have also been made to investigate the anti - inflammatory and anti - oxidant activity of the synthesized AgNPs. Anti - oxidant activit y was assessed using DPPH method. Anti - inflammatory potential was evaluated through in vitro inhibition of protein denaturation, protease activity and improved membrane stabilization property . |
| Databáze: | OpenAIRE |
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