The clinical manifestations of the five cases of lymphangitic carci-nomatosis of the lung presented as diffuse and interstitial disease
| Autor: | Bong Chun Lee, Yeon Lim Seo, Dong Soon Kim, Young Joo Sung, Soo Jeon Choi |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Pathology Lung medicine.diagnostic_test business.industry Interstitial lung disease respiratory system medicine.disease Primary tumor respiratory tract diseases Pulmonary function testing Infectious Diseases Bronchoalveolar lavage medicine.anatomical_structure Lymphangitic Carcinomatosis medicine Radiology Lung cancer business Interstitial Disease |
| Zdroj: | Tuberculosis and Respiratory Diseases. 39:55-61 |
| ISSN: | 2005-6184 1738-3536 |
| Popis: | Background: The lung is the most common site of metastasis and usually it manifests as a single or multiple nodules in chest X-ray. But less commonly the cancer spreads through the lymphatics and X-ray shows diffuse reticulonodular densities. Sometimes, patient is presented with respiratory symptoms only with interstitial lung infiltration before the signs of primary tumor and in that cases, the differential diagnosis with other interstitial lung disease is required. We have experienced 5 such cases, who were diagnosed as lymphangitic carcinomatosis by transbronchial lung biopsy. Methods: Clinical manifestation, pulmonary function test, modified thin section CT, bronchoalveolar lavage and transbronchial lung biopsy were done. Results: The primary tumor was gastric cancer in 3, lung cancer in 2. Pulmonary function test showed restrictive pattern with low DLco in 2 patients and obstructive pattern in one. Bronchoalveolar lavage showed lymphocytosis in 4 patients and malignant cells were found in one patient. Transbronchial lung biopsy revealed malignant cells localized to the lymphatics (peribronchial, perivascular and perialveolar). Cell type was adenocarcinoma in 4 and squamous cell carcinoma in one. Conclusion: Rarely lymphangitic carcinomatosis can be presented as diffuse interstitial lung disease and easily diagnosed by transbronchial lung biopsy. |
| Databáze: | OpenAIRE |
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