Nevus psiloliparus: Newly described histopathological features from transverse sections

Autor:	Vikash S. Oza, Nicholas A. Taylor, Jorge Roman, Randie H. Kim
Rok vydání:	2020
Předmět:	Pathology medicine.medical_specialty Histology business.industry Fibroblast growth factor receptor 1 Dermatology medicine.disease Pathology and Forensic Medicine 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Dermis 030220 oncology & carcinogenesis Scalp Encephalocraniocutaneous Lipomatosis medicine Nevus Histopathology skin and connective tissue diseases business Nevus psiloliparus Congenital Alopecia
Zdroj:	Journal of Cutaneous Pathology. 47:633-637
ISSN:	1600-0560 0303-6987
DOI:	10.1111/cup.13663
Popis:	Nevus psiloliparus is a rare fatty tissue nevus that is a marker for encephalocraniocutaneous lipomatosis, a neurocutaneous syndrome with ocular and central nervous system anomalies. Clinically, nevus psiloliparus is often described as a congenital alopecia and appears as an irregularly shaped, circumscribed area of alopecia on the scalp. Histopathology demonstrates a near-complete absence of mature hair follicles with preservation of arrector pili muscles and mature adipocytes within the dermis. The pathogenesis of nevus psiloliparus may be related to mosaic mutations in fibroblast growth factor receptor 1. Herein we report the histopathological features of a nevus psiloliparus in an 11-year-old girl diagnosed from transverse sections, which show "shadow" follicular units characterized by columns of loosely arranged collagen and a relative paucity of elastic fibers.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bfba263ca565f2e8e316f049c316d5b2 https://doi.org/10.1111/cup.13663 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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