Biological effects of 6-methyl-Δ5-androstene-3β-ol-17-one
| Autor: | Evelyn Howard |
|---|---|
| Rok vydání: | 1965 |
| Předmět: |
Pharmacology
medicine.medical_specialty genetic structures Organic Chemistry Clinical Biochemistry Epiphyseal fusion Preputial gland food and beverages Ovary Biology Biochemistry chemistry.chemical_compound Endocrinology medicine.anatomical_structure chemistry Internal medicine medicine lipids (amino acids peptides and proteins) Molecular Biology Methyl group |
| Zdroj: | Steroids. 5:255-259 |
| ISSN: | 0039-128X |
| DOI: | 10.1016/0039-128x(65)90088-7 |
| Popis: | Androgenic activity with respect to the phallus and preputial glands was exhibited by 6-methyl-DHA, but this was significantly less than the androgenic activity of DHA. No effect of 6-methyl-DHA on the rate of epiphyseal fusion was detected under conditions in which DHA was active. The methyl group at C-6 was found to completely block the estrogenic action that the parent compound exhibits in immature mice in the presence of the ovary. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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