| Autor: |
L Morales Martinez, C Saez Bertrand, B Reques, G. Sevilla Santos, M Blasco Guerrero, C Martín Blas |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Section 4: Clinical Pharmacy Services. |
| DOI: |
10.1136/ejhpharm-2019-eahpconf.221 |
| Popis: |
Background Dose adjustment according to estimated glomerular filtration rate (eGFR) in patients with renal failure (RF) is important in avoiding adverse effects, and changes in the intensity and duration of the pharmacological effect. Purpose To assess the level of compliance with anti-infective drug dosage adjustments in RF patients. To discover the most frequent errors considering type of anti-infective, type of error and group of patients according to eGRF. Material and methods A prospective observational descriptive study between 1–30 September 2018 was conducted. Inclusion criteria: RF adult patients (defined as eGFR Results One-hundred and four patients were included, 56.7% women (mean age 77.5±13.1 years). One-hundred and fifteen prescriptions were revised. 80.8% of prescriptions corresponded to medical services (MS) and 19.2% to surgical services (SS). 21.7% of total prescriptions were uncorrected. Twenty-seven prescription errors were shown (21.5% errors in MS prescriptions and 22.8% in SS prescriptions): 77% were dose regimen errors and 22% dose errors. Table 1 and 2 show distributions according to eGFR and anti-infective agents. Conclusion Detection and error rate of 21.7% is a considerably high value. Prescription errors are directly related to type of dosage adjustment described for each anti-infectious drug. No significant differences between MS and SS in dosage adjustment were observed. Patients with more errors in the prescription were those whose eGFR was in the groups 50–30 and 29–10 ml/min. Incorporating alert systems to identify RF patients and anti-infectives requiring adjustments, and to provide educational lectures in MS and SS are required. Pharmaceutical intervention programmes are a support tool for the correct anti-infective drugs prescription in RF patients. References and/or acknowledgements No conflict of interest. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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