Pre- and Postnatal Lung Development: An Updated Species Comparison
| Autor: | Mark E. Hurtt, Geertje Lewin |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Postnatal Care Embryology medicine.medical_specialty Lung Health Toxicology and Mutagenesis Functional testing Experimental Animal Models Human airway Biology Toxicology Human situation 03 medical and health sciences Functional development 030104 developmental biology 0302 clinical medicine medicine.anatomical_structure 030228 respiratory system Pediatrics Perinatology and Child Health Immunology medicine Respiratory function Intensive care medicine Developmental Biology |
| Zdroj: | Birth Defects Research. 109:1519-1539 |
| ISSN: | 2472-1727 |
| DOI: | 10.1002/bdr2.1089 |
| Popis: | The purpose of this review is to give an outline of respiratory tract morphological and functional development with an emphasis on perinatal and postnatal maturational processes. In view of the rising need for qualitative and quantitative data for the development of pediatric pharmaceuticals, a comparison of the human situation to experimental animal models is made, and functional data as well as suitable models for human airway diseases and functional testing are presented. Birth Defects Research 109:1519-1539, 2017. © 2017 Wiley Periodicals, Inc. |
| Databáze: | OpenAIRE |
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