Characterization of nisin containing chitosan-alginate microparticles

Autor: John N. Coupland, Ramaswamy C. Anantheswaran, Vaishnavi Chandrasekar
Rok vydání: 2017
Předmět:
Zdroj: Food Hydrocolloids. 69:301-307
ISSN: 0268-005X
DOI: 10.1016/j.foodhyd.2017.02.011
Popis: Nisin is a naturally occurring bacteriocin that has GRAS status for use in foods granted by the FDA. Encapsulation of nisin within microparticles can protect it from interactions with other food components, thereby increasing its stability and functionality. The effects of formulation parameters on the physico-chemical characteristics of nisin-loaded chitosan-alginate microparticles were studied. Chitosan-alginate microparticles were prepared using the ionotropic pre-gelation method, which involves inducing coiling of the alginate polymer by forming a calcium-alginate pre-gel state, and followed by chitosan complexation. Calcium-alginate pre-gel states were investigated using various calcium concentrations (0–5 mM) through viscosity measurements, and calcium concentrations below 2 mM were found to promote the formation of a coiled alginate nucleus. Calcium concentration had a significant effect (p
Databáze: OpenAIRE