Effects Of (1→3), (1→6)-β-D-Glucan Behavior in Human Dermal Fibroblast Cells under Serum Starvation

Autor: Yeon I Woo, Hyun Joo Son, Hye Ryeon Lim, Mi Hee Lee, Hyun Sook Baek, Kazufumi Tsubaki, Jong Chul Park
Rok vydání: 2007
Předmět:
Zdroj: Key Engineering Materials. :401-404
ISSN: 1662-9795
DOI: 10.4028/www.scientific.net/kem.342-343.401
Popis: Glucans have been reported to stimulate immunity and to promote wound healing. Adult human dermal fibroblast (aHDF) cultured in serum free (serum-starvation). Proliferation of aHDF was measured at various concentrations of β-glucan by MTT assay, and migration was observed for 36h on microscope. The result of fibroblast bioassay, β-glucan had positive influence. In this study, the direct effects of β-glucan on proliferation and migration of human dermal fibroblasts were examined in vitro. That means β-D-glucan has the effect to enhance proliferation and aHDF migration speed, and has the potential as a wound healing agent.
Databáze: OpenAIRE