A probably isolated subclavicular lymphadenopathy in acute leukemia: An unusual localisation of cryptococcosis

Autor:	M. Medhaffar, L. Kammoun, I. Maaloul, M. Elloumi, L. Ayadi, H. Harrabi
Rok vydání:	2010
Předmět:	Cryptococcus neoformans Pathology medicine.medical_specialty Acute leukemia biology medicine.diagnostic_test Cancer biology.organism_classification medicine.disease Infectious Diseases Cryptococcosis Biopsy medicine Complication Fluconazole Mycosis medicine.drug
Zdroj:	Journal de Mycologie Médicale. 20:227-230
ISSN:	1156-5233
DOI:	10.1016/j.mycmed.2010.07.001
Popis:	Summary Introduction Cryptococcus neoformans ( C. neoformans ) is a fungal opportunistic pathogen which infects immunocompromised patients, especially those who are seropositive for the human immunodeficiency virus (HIV) and those with lymphoproliferative malignancies. Lungs and meninx are the most frequently involved sites, but isolated lymph nodes are less infected. Case report We report the observation of an 18-year-old-patient, receiving chemotherapy for a lymphoblastic acute leukemia, who developed an isolated subclavicular lymphadenopathy. The diagnosis of cryptococcal lymphadenitis was confirmed by fine needle aspiration cytology and biopsy. Surgery and fluconazole allowed a favourable outcome. Conclusion Isolated cryptococcal lymphadenopathy is a rare complication that occurs in patients with hematological malignancies. The diagnosis is based on culture and/or fine needle aspiration cytology and/or biopsy. The prognosis is favourable with surgical treatment and antifungal therapy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bf82c787f5d507f45cfb329c9c12049a https://doi.org/10.1016/j.mycmed.2010.07.001 Zobrazit plný text záznamu Full Text from ScienceDirect