Effects of age, menopause and human growth hormone on variables of fibrinolysis
| Autor: | Helmut Schulte, Gerd Assmann, Astrid Dirkes-Kersting, Joachim Heinrich |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
medicine.medical_specialty
business.industry Plasminogen Activator Inhibitor Type 1 medicine.medical_treatment Human growth hormone Hematology medicine.disease Tissue plasminogen activator Menopause Endocrinology Ageing Internal medicine Fibrinolysis Epidemiology medicine business medicine.drug Hormone |
| Zdroj: | Fibrinolysis. 6:33-35 |
| ISSN: | 0268-9499 |
| DOI: | 10.1016/0268-9499(92)90012-7 |
| Popis: | The relationships between the fibrinolytic system and changing hormone levels, due to ageing and menopausal status, were investigated in 1140 healthy participants of a large scale, epidemiological study. Tissue plasminogen activator and euglobulin fibrinolysis activity were found to decrease with age and after the onset of menopause, whereas plasminogen activator inhibitor type 1 increased. The latter variable also showed a significant negative correlation to human growth hormone. The lower fibrinolytic activity of older men and postmenopausal women is in accordance with their higher coronary risk. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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