Aggregation of features of the metabolic syndrome is associated with increased prevalence of chronic complications in Type 2 diabetes
| Autor: | Luciana A. Costa, Luis Henrique Santos Canani, Hugo Roberto Kurtz Lisboa, Jorge Luiz Gross, Glaucia Sarturi Tres |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
medicine.medical_specialty
business.industry Endocrinology Diabetes and Metabolism Type 2 Diabetes Mellitus Diabetic retinopathy Type 2 diabetes medicine.disease Gastroenterology Surgery Coronary artery disease Endocrinology Diabetes mellitus Internal medicine Internal Medicine medicine Microalbuminuria Metabolic syndrome business Retinopathy |
| Zdroj: | Diabetic Medicine. 21:252-255 |
| ISSN: | 0742-3071 |
| DOI: | 10.1111/j.1464-5491.2004.01124.x |
| Popis: | Aims To investigate the association of features of the metabolic syndrome with the prevalence of chronic complications. Methods A cross-sectional study was conducted with 548 patients with Type 2 diabetes mellitus (DM). Metabolic syndrome was diagnosed in the presence of at least two of the following: hypertension, dyslipidaemia, obesity, and microalbuminuria. Results Patients with the metabolic syndrome (85%) had a higher prevalence of peripheral vascular disease (PVD) (35% vs. 18%), retinopathy (44% vs. 20%), distal sensory neuropathy (DSN) (44% vs. 24%), micro- and macroalbuminuria (38% vs. 28%) and coronary artery disease (CAD) (53% vs. 36%). The more metabolic syndrome features (none/one, two, three or four), the higher the proportion of diabetes complications: PVD 18%, 31%, 37% and 38%; stroke 1.0%, 4.5%, 5.9% and 11.3%; retinopathy 20%, 38%, 42% and 64%; DSN 24%, 32%, 49% and 57%; micro- and macroalbuminuria 28%, 36% and 41%; and CAD 36%, 44%, 52% and 60% (P |
| Databáze: | OpenAIRE |
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