Absolute configuration of two novel compounds from the Talaromyces aculeatus using optical rotation, electronic circular dichroism and vibrational circular dichroism
| Autor: | Shuang-Shuang Ding, Qin Yang, Can-Can Zhang, Miao-Miao Liang, Yan Li, Wen-Si Shi, Hua-Jie Zhu |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Circular dichroism
010405 organic chemistry Organic Chemistry Absolute configuration 01 natural sciences Biochemistry 0104 chemical sciences 010404 medicinal & biomolecular chemistry chemistry.chemical_compound Crystallography chemistry Drug Discovery Vibrational circular dichroism Talaromyces aculeatus Optical rotation Fermentation broth Derivative (chemistry) |
| Zdroj: | Tetrahedron Letters. 57:75-79 |
| ISSN: | 0040-4039 |
| DOI: | 10.1016/j.tetlet.2015.11.066 |
| Popis: | Two novel compounds (1-2), together with two known compounds 3 (Pinophilins B) and 4 (Sch 725680) were isolated from the fermentation broth of fungus of Talaromyces aculeatus (DS-62013). Absolute configuration (AC) of compound 1 was deduced by comparison of experimental and calculated optical rotation (OR), electronic circular dichroism (ECD), and vibrational circular dichroism (VCD) with those of its derivative la. Since both OR and ECD methods cannot provide the convincible data for AC identification, and VCD was used in the AC study. The AC of compound 2 was also determined. (C) 2015 Elsevier Ltd. All rights reserved. |
| Databáze: | OpenAIRE |
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