Effect of Biotic and Abiotic Factors on the Biofilm Formation in Gram-Negative Non-fermenting Bacteria

Autor: Elena A. Vereshak, Iraida S Aleshukina, Elena V. Goloshva, Zinaida M. Kostoeva, Andrey Gorovtsov, Anna V. Aleshukina
Rok vydání: 2020
Předmět:
Zdroj: Nanotechnology in the Life Sciences ISBN: 9783030403362
Popis: Biofilm microorganisms are protected from the adverse factors of a physical, chemical, and biological nature, which include temperature effects, desiccation, ultraviolet radiation, antibiotics, disinfectants, and humoral and cellular factors of the immune system. Therefore, in recent years, a new strategy in the treatment of infections associated with biofilms is the search for the means of destroying the biofilms of bacteria. The chapter highlights the current understanding of the biofilm-forming ability of bacteria with an emphasis on this property in non-fermentative bacteria. Long-term monitoring of the circulation of these microorganisms indicates their stable detection among the dominant potential pathogens associated with the provision of medical care. The results of studies of biofilm formation among the detected non-fermenting bacteria are presented. The possibilities of mass spectrometric analysis in the selection of effective disinfectants in hospitals are shown.
Databáze: OpenAIRE