Autor: |
Hocine Laouer, Soulaf Mehlous, Chahrazed Kaoudoune, Smain Amira, Fatima Benchikh, Hassiba Benabdallah, Karima Loucif |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
Journal of Drug Delivery and Therapeutics. 10:188-190 |
ISSN: |
2250-1177 |
Popis: |
This study aimed to estimate the total phenolic and flavonoid contents and to evaluate the antioxidant activity of the Hydro-methanolic from Saccocalyx satureioides Coss and Dur aerial part. Total polyphenols contents were determined using Folin-Ciocalteu’s reagent. The flavonoids were estimated using the method of Aluminum chloride (AlCl3). The antioxidant capacity was evaluated using two in vitro models (the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and reducing power). Total phenolic and flavonoid content in the extract were 171.34 ±1.43 mg Gallic acid equivalent/g of dry extract (GAE/g) and 18.6 ± 0.46 mg Quercetin equivalent / g of dry extract (QE/g), respectively. The methanol extract has an important capacity to scavenge the free radical DPPH with an IC50 of 0.03 ± 0. 0024 mg/ml. In addition, the plant extract exhibited high reducing power with an IC50 of 0.54 ± 0.00625 mg/ml. The results of the present study may prove that the medicinal plants are a good resource of natural antioxidants. Keywords: Antioxidant activity, Saccocalyx satureioides, polyphenols, flavonoids. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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