Experimental vaccination of rainbow trout against Loma salmonae using a live low-virulence variant of L. salmonae
Autor: | R. J. F. Markham, Simon R. M. Jones, J. G. Sanchez, D. J. Speare |
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Rok vydání: | 2001 |
Předmět: | |
Zdroj: | Journal of Fish Biology. 59:442-448 |
ISSN: | 1095-8649 0022-1112 |
DOI: | 10.1111/j.1095-8649.2001.tb00142.x |
Popis: | Prior exposure of rainbow trout Oncorhynchus mykiss juveniles to the low-virulence variant of Loma salmonae, L. salmonae SV, spores resulted in a xenoma intensity in the gill filaments fourteen times lower (0.044 v. 0.641 xenomas per filament; P=0.0001) than that observed in the naive controls, challenged with L. salmonae spores, as determined morphometrically by in situ hybridization at the peak of the disease (between 4 and 6 weeks post exposure). The marked degree of reduction in numbers of xenomas that formed after challenge suggests that use of the low-virulence variants should be further considered as a means to protect fish in regions where the parasite is endemic, to protect them during grow out periods. |
Databáze: | OpenAIRE |
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