Reliability of the INSTI® rapid test for the diagnosis of HIV-1 non-B subtypes and recombinant variants
| Autor: | Aurélie Guigon, Laurent Bélec, Anne Languille, Thierry Prazuck, Laurent Hocqueloux, G. Giraudeau, Jeanne Goupil de Bouillé, David Plainchamp, Gwenaël Le Moal, Aurelie Theillay |
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| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
biology business.industry Human immunodeficiency virus (HIV) virus diseases Test sensitivity medicine.disease_cause Hiv subtype 030112 virology Virology Test (assessment) law.invention 03 medical and health sciences Infectious Diseases law Immunology medicine Recombinant DNA biology.protein Antibody business |
| Zdroj: | Journal of Medical Virology. 88:180-183 |
| ISSN: | 0146-6615 |
| Popis: | Data regarding the efficacy of Rapid HIV tests (RHTs) in detecting non-B subtype HIV-1 are limited. We evaluated the sensitivity of the INSTI® test for the detection of HIV-1 antibodies for the diagnosis of HIV-1 non-B subtypes and recombinant variants. We identified adults with HIV-1 infection due to non-B subtypes and recombinant variants. The participants were re-tested with INSTI® test. We included 258 patients. Overall, the INSTI® test sensitivity was 98.4% (95%CI: 96.9–99.9%). For the major CRF_02AG subtype, the sensitivity was 99.0% (95%CI: 97.1–100%). The HIV INSTI® test is reliable for the detection of various non-B HIV-1 antibodies. J. Med. Virol. 88:180–183, 2016. © 2015 Wiley Periodicals, Inc. |
| Databáze: | OpenAIRE |
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