Free Radical Methodology for Carbohydrate to Carbocycle Transformations: An Efficient Synthesis of the Tricyclic Dihydrofuran Portion of Azadirachtin

Autor:	Bert Fraser-Reid, Kenneth J. Henry
Rok vydání:	1994
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Azadirachtin chemistry Intramolecular reaction Hydride Organic Chemistry Acetal Organic chemistry Stereoselectivity Radical cyclization Lactone Tricyclic
Zdroj:	The Journal of Organic Chemistry. 59:5128-5129
ISSN:	1520-6904 0022-3263
Popis:	Iodo lactone (6b), derived from D-galactal, undergoes tin hydride medi- ated transannular radical cyclization to give the tricyclic lactone (7), which is easily converted into an advanced precursor of the tricyclic dihydrofuran portion of the potent insect antifeedant azadirachtin (1)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bee4a96990b4a59c6c3ba8d8eb05c5af https://doi.org/10.1021/jo00097a007 Zobrazit plný text záznamu