ChemInform Abstract: Efficient Total Synthesis of Racemic and Optically Active Cyclobut-A and Simple Analogues

Autor:	Adam W. Sledeski, Michael E. Jung
Rok vydání:	2010
Předmět:	chemistry.chemical_compound chemistry Acetylene Yield (chemistry) Maleic anhydride Total synthesis Purine derivative General Medicine Optically active Combinatorial chemistry
Zdroj:	ChemInform. 24
ISSN:	0931-7597
DOI:	10.1002/chin.199329168
Popis:	Rapid synthesis of the potent antiviral agent, cyclobut-A, 1a, from the inexpensive starting materials maleic anhydride and acetylene, in both racemic and optically active forms, is described; the route also allows for the preparation of several hydroxylated and keto analogues in good overall yield.
Databáze:	OpenAIRE
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