Soft tissue sarcomas & GIST
Autor: | Sophie Roider-Schur, Thomas Brodowicz, Rainer Hamacher |
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Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
Oncology Pathology medicine.medical_specialty Treatment response GiST business.industry Soft tissue sarcoma medicine.medical_treatment Optimal treatment Soft tissue Hematology Disease Immunotherapy medicine.disease 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis Internal medicine medicine Conventional chemotherapy business |
Zdroj: | memo - Magazine of European Medical Oncology. 9:207-210 |
ISSN: | 1865-5076 1865-5041 |
DOI: | 10.1007/s12254-016-0287-z |
Popis: | Soft tissue sarcomas (STS) are a rare and heterogeneous disease sharing mesenchymal origin. While classification of different STS subtypes has generated insight into their molecular pathogenesis, treatment response, and prognosis, oncological management still poses major clinical challenges. Despite considerable evolution in definition of optimal treatment strategies over the past decade there is a critical need of new and less toxic therapeutic approaches for the treatment of metastatic sarcoma. This review covers the latest clinical study highlights for soft tissue sarcomas and gastroinestinal stromal tumours (GIST) presented at ASCO 2016, demonstrating a constant progress from conventional chemotherapy to histology-tailored therapy as well as immunotherapy approaches. |
Databáze: | OpenAIRE |
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