Atomic force microscopy of swelling and hardening of intact erythrocytes fixed on substrate
| Autor: | A. V. Ankudinov, K. I. Timoshchuk, T. E. Timoshenko, M. M. Khalisov |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Materials science Physics and Astronomy (miscellaneous) Atomic force microscopy Nanotechnology 02 engineering and technology 03 medical and health sciences 020303 mechanical engineering & transports 030104 developmental biology 0203 mechanical engineering Hardening (metallurgy) Biophysics medicine Swelling medicine.symptom |
| Zdroj: | Technical Physics. 62:310-313 |
| ISSN: | 1090-6525 1063-7842 |
| DOI: | 10.1134/s1063784217020116 |
| Popis: | Peak force measurements with the aid of atomic force microscopy are used to quantitatively map nanomechanical properties of intact erythrocytes of rats under conditions that are close to physiological conditions. Erythrocytes that are immobilized on the substrate preliminary processed using poly-L-lysine predominantly exhibit plane shape. However, cells may also exhibit stepwise transformation to semispherical objects with an increase in volume and hardening. Possible reasons for such transformations are discussed. |
| Databáze: | OpenAIRE |
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