| Autor: | Karen Ratliff-Schaub, Chris Weinle, Jeanne B. Funk, Melissa Myers, Tracy C. Carey, Jennifer Jenks |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Placebo-controlled study medicine.disease Placebo Secretin Developmental disorder Endocrinology Multivariate analysis of variance Gastrointestinal hormone El Niño Internal medicine Developmental and Educational Psychology medicine Autism Psychology hormones hormone substitutes and hormone antagonists |
| Zdroj: | Journal of Autism and Developmental Disorders. 32:161-167 |
| ISSN: | 0162-3257 |
| DOI: | 10.1023/a:1015493412224 |
| Popis: | Secretin has been proposed as a treatment alternative for autistic spectrum disorders, but empirical support is lacking. A double-blind placebo-controlled study examined the effect of a single dose of synthetic human secretin on aberrant behavior. Parent and teacher data from the Aberrant Behavior Checklist for eight male children were analyzed for reliable change in a clinical replication series. By parent and teacher report, the majority of change occurred either on the placebo trial or reflected deterioration subsequent to secretin infusion. Repeated-measures multivariate analysis of variance results were similar. Results are consistent with other studies, suggesting that secretin may not be an effective treatment option. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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