ICR gene signature to identify differential immune landscapes in anatomic subsites of head and neck squamous cell carcinomas and implications in personalized medicine

Autor:	Manish R. Patel, Dong M. Shin, Lori J. Wirth, Rom Leidner, Jong Chul Park, Mihir R. Patel, Kyle Halliwell, Francesco M. Marincola, Daniel R. Clayburgh, Derrick T. Lin, Debra Chao, Belinda Cairns, Bevan Yueh, Josue Samayoa, Richard Bryan Bell, Tolga Turan, Nabil F. Saba, Sara I. Pai, Naomi Fujioka, Daniel E. H. Afar
Rok vydání:	2018
Předmět:	Cancer Research business.industry Immune checkpoint inhibitors Cell Gene signature medicine.disease Head and neck squamous-cell carcinoma stomatognathic diseases 03 medical and health sciences 0302 clinical medicine Immune system medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis polycyclic compounds medicine Cancer research Single agent Personalized medicine Head and neck business hormones hormone substitutes and hormone antagonists 030215 immunology
Zdroj:	Journal of Clinical Oncology. 36:6052-6052
ISSN:	1527-7755 0732-183X
DOI:	10.1200/jco.2018.36.15_suppl.6052
Popis:	6052Background: Head and neck squamous cell carcinoma (HNSCC) patients have a 16-25% response rate to single agent immune checkpoint inhibitors (ICI). Prognostic biomarkers to ICIs are needed to id...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::be99aa0f5547d6047ab3c7ba8c029fe7 https://doi.org/10.1200/jco.2018.36.15_suppl.6052 Zobrazit plný text záznamu