Profound Thrombocytopenia after Treatment with Tirofiban; On-Pump Surgery for Acute Aortic Dissection and Coronary Bypass Surgery
| Autor: | Poelaert Jan, Demanet C, Jochmans K, Van Der Meeren Sam, Remory Isabel, Bougie Daniel, Beckers Stefan |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Aortic dissection
medicine.medical_specialty Acute coronary syndrome business.industry General Medicine Tirofiban medicine.disease Surgery Coronary artery disease medicine.anatomical_structure Bypass surgery Aortic valve replacement hemic and lymphatic diseases Internal medicine Cardiology Medicine Platelet business medicine.drug Artery |
| Zdroj: | Cardiovascular Pharmacology: Open Access. 2 |
| ISSN: | 2329-6607 |
| DOI: | 10.4172/2329-6607.1000105 |
| Popis: | We describe the case of a 69-year-old man who developed glycoprotein IIb/IIIa receptor (GPIIb/IIIa) antagonist associated thrombocytopenia and the successful management during urgent aortic dissection and coronary artery bypass grafting. A flow cytometric assay was developed to confirm the diagnosis of GPIIb/IIIa-antagonist induced thrombocytopenia. This case was further complicated by the concomitant presence of heparine/PF4 platelet antibodies, but was proven not to be the causal factor of the thrombocytopenia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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