Bone calcium content and biomechanics in a spontaneous hypertensive/NIH corpulent rat ( )

Autor:	P.B Moser-Veillon, S Yamini, B Szepesi, Otho E. Michaelis
Rok vydání:	1995
Předmět:	Bone growth medicine.medical_specialty Sucrose Starch Magnesium Biomechanics chemistry.chemical_element General Medicine Urinary calcium Bone remodeling chemistry.chemical_compound Endocrinology chemistry Internal medicine medicine Bone calcium
Zdroj:	Comparative Biochemistry and Physiology Part A: Physiology. 112:425-431
ISSN:	0300-9629
DOI:	10.1016/0300-9629(95)02010-1
Popis:	This study was undertaken to determine the calcium content and bone biomechanics in SHR N-cp rat. Obese and lean male SHR N-cp rats were given diets containing either 54% sucrose or starch or a combination of 18% sucrose plus 36% starch for a period of 8 months. Urinary calcium, magnesium and phosphorus levels were greater in obese rats than in lean rats and were exaggerated by the 54% sucrose diet. Obese rats had significantly shorter and smaller femurs, lower breaking strength, and lower bone calcium and magnesium concentrations than lean littermates. No significant diet effect was observed on any of the bone parameters. Obese SHR N-cp rats appear to have disorders with bone growth, which may be useful for understanding of altered bone metabolism in the diabetic state.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::be781effed574ab1403731132860904a https://doi.org/10.1016/0300-9629(95)02010-1 Zobrazit plný text záznamu