Housing and Environment

Autor: Jack R. Hessler, Robert E. Faith
Rok vydání: 2006
Předmět:
Zdroj: The Laboratory Rat ISBN: 9780120749034
DOI: 10.1016/b978-012074903-4/50013-3
Popis: Publisher Summary Research animals respond to many factors, or changes in their environment. These responses may affect experimental results. The greater the understanding of the effects that environmental elements can have on biological processes, the better the variables can be controlled, or at least the better experimental results can be discussed in light of them. A constant, reproducible environment (to within the prescribed limits) is desirable to minimize the physiological variations associated with environmental changes; however, the effective control of all environmental variables at all times is a difficult goal. However, all reasonable attempts should be made to control those environmental factors most likely to interfere with the work in progress. Records should be kept of environmental variables relevant to the research programs in the facility. Planned significant environmental changes should not be made without prior consultation with the investigators to ensure that minimal impact occurs to research programs. A cardinal rule of laboratory animal science and medicine is to always keep in mind that procedures carried out in health and husbandry programs may have significant effects on research results.
Databáze: OpenAIRE