RNA-Seq DE Genes on Glioblastoma Using Non Linear SVM and Pathway Analysis of NOG and ASCL5
| Autor: | Sandra Binoy, C. M. Prashanth, Blessy Baby Mathew, Cynthia Basilia, Vinai George Biju |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Intracranial tumor Computer science RNA-Seq Computational biology Pathway analysis medicine.disease 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Differentially expressed genes 030220 oncology & carcinogenesis Glioma Gene expression medicine Gene Glioblastoma |
| Zdroj: | Computational Vision and Bio-Inspired Computing ISBN: 9783030372170 |
| Popis: | Differentially Expressed genes related to Glioblastoma Multiforme as an output of RNASeq studies were further studied to conclude new research insights. Glioma is a type of intracranial tumor (within the skull), which can grow rapidly in its malignant stages. Gene expression in Grade II, III and IV Gliomas is analysed using non linear SVM models. The enriched GO terms were identified GOrilla. Pathways related to NOG and ASCL5 gene were studied using Reactome. |
| Databáze: | OpenAIRE |
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