Autor: |
Alla S. Koltsova, Mikhail I. Krapivin, Andrei V. Tikhonov, Vladislav S Baranov, V Kh Khavinson, Olga A. Efimova, Lubov’ I. Petrova, Anna A. Pendina, Natalia Linkova, Anastasiia V. Petrovskaia-Kaminskaia |
Rok vydání: |
2019 |
Předmět: |
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Zdroj: |
Medical academic journal. 19:166-168 |
ISSN: |
1608-4101 |
DOI: |
10.17816/maj191s1166-168 |
Popis: |
The goal of the research is to study the effect of KE peptide on telomere length of PHA-stimulated blood lymphocytes of young and middle-aged men. 11 blood lymphocyte samples were enrolled in the analysis. Relative telomere length was measured using fluorescence in situ hybridization with DNA-probes specific to telomere sequences of human chromosomes. 5 cases of significant telomere length alteration were registered. These changes were more frequent registered in middle-aged people: 4 invents cases versus 1. KE peptide increased telomere length in blood lymphocytes of middle-aged people if it was basically low and, vice versa, decreased the basically high telomere length. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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