Allergic Bronchopulmonary Aspergillosis due to Aspergillus niger without Bronchial Asthma
| Autor: | Takashi Shibusa, Hideaki Hoshino, Akihisa Fujita, Hirotsugu Takabatake, Kyuichiroh Sekine, Shosaku Abe, Shigeru Tagaki, Hayato Kon |
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| Rok vydání: | 1999 |
| Předmět: |
Pulmonary and Respiratory Medicine
Allergy biology business.industry biology.organism_classification medicine.disease Immunoglobulin E Aspergillosis respiratory tract diseases Aspergillus fumigatus Immunology medicine biology.protein Sputum Methacholine medicine.symptom Allergic bronchopulmonary aspergillosis business medicine.drug Asthma |
| Zdroj: | Respiration. 66:369-372 |
| ISSN: | 1423-0356 0025-7931 |
| DOI: | 10.1159/000029392 |
| Popis: | A 65-year-old woman was admitted to our hospital with a dry cough and pulmonary infiltrates. Chest radiograph and CT revealed mucoid impaction and consolidations. Peripheral blood eosinophilia and elevated serum IgE were observed. Aspergillus niger was cultured repeatedly from her sputum, but A. fumigatus was not detected. Immediate skin test and specific IgE (RAST) to Aspergillus antigen were positive. Precipitating antibodies were confirmed against A. niger antigen, but not against A. fumigatus antigen. She had no asthmatic symptoms, and showed no bronchial hyperreactivity to methacholine. Thus, this case was diagnosed as allergic bronchopulmonary aspergillosis (ABPA) without bronchial asthma due to A. niger, an organism rarely found in ABPA. The administration of prednisone improved the symptoms and corrected the abnormal laboratory findings. |
| Databáze: | OpenAIRE |
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