A Flexible, Efficient Synthesis of (±)-Carbocyclic Phosphonic Acid Nucleoside Derivatives

Autor: Pei-Pei Kung, Sutton Scott Channing, Peter S. Dragovich, Andrew Lund, Adrian Maddaford, Donald Stuart Middleton, David Leese, Richard A. Bissell, Phillip Wainwright, Ray Fisher, Javier Gonzalez, David C. Pryde, Peter T. Stephenson, Karen Runcie
Rok vydání: 2005
Předmět:
Zdroj: Synlett. :0765-0768
ISSN: 1437-2096
0936-5214
DOI: 10.1055/s-2005-863745
Popis: An efficient and flexible synthesis of cyclopentane and hydroxylated cyclopentane phosphonic acid analogues is described. The key step involves the opening of an epoxide with either a nucleoside base or a selenyl anion toaccess the target molecules.
Databáze: OpenAIRE