A Flexible, Efficient Synthesis of (±)-Carbocyclic Phosphonic Acid Nucleoside Derivatives
Autor: | Pei-Pei Kung, Sutton Scott Channing, Peter S. Dragovich, Andrew Lund, Adrian Maddaford, Donald Stuart Middleton, David Leese, Richard A. Bissell, Phillip Wainwright, Ray Fisher, Javier Gonzalez, David C. Pryde, Peter T. Stephenson, Karen Runcie |
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Rok vydání: | 2005 |
Předmět: | |
Zdroj: | Synlett. :0765-0768 |
ISSN: | 1437-2096 0936-5214 |
DOI: | 10.1055/s-2005-863745 |
Popis: | An efficient and flexible synthesis of cyclopentane and hydroxylated cyclopentane phosphonic acid analogues is described. The key step involves the opening of an epoxide with either a nucleoside base or a selenyl anion toaccess the target molecules. |
Databáze: | OpenAIRE |
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