Selective inhibition of the pacemaker channel If improves symptoms in severe dilated cardiomyopathy
| Autor: | Erland Erdmann, Robert Larbig, Karl La Rosée, Uta C. Hoppe |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Inotrope
medicine.medical_specialty Sinus tachycardia business.industry Dilated cardiomyopathy General Medicine medicine.disease Myasthenia gravis Heart failure Internal medicine medicine Cardiology Verapamil medicine.symptom Cardiology and Cardiovascular Medicine business Ivabradine Asthma medicine.drug |
| Zdroj: | Clinical Research in Cardiology. 96:243-246 |
| ISSN: | 1861-0692 1861-0684 |
| Popis: | Karl La Rosee Kardiologische Gemeinschaftspraxis Bonn, Germany Sirs: Systolic heart failure is a common health problem world wide. Due to sympathetic activation heart failure patients generally develop an elevated heart rate, which further deteriorates pathological changes and symptoms in a circulus vitiosus. Interruption of this circle is an important mechanism of beta-blocker therapy in heart failure. However, there may be several contraindications to beta-blockers like asthma bronchiale. For these patients so far no reasonable alternative medication is available, particularly because verapamil should not be given due to its marked negative inotropic effect. We present a patient with severe myasthenia gravis, dilated cardiomyopathy and sinus tachycardia, who was markedly improved by the selective If inhibitor ivabradine. Case report |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink