Synthetic Materials for Osteochondral Tissue Engineering
| Autor: | Antoniac Vasile Iulian, Laptoiu Dan, Gradinaru Sebastian, Milea Claudia, Tecu Camelia |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Scaffold Engineering Biocompatibility business.industry Hyaline cartilage Cartilage Biomaterial 02 engineering and technology 021001 nanoscience & nanotechnology 03 medical and health sciences 030104 developmental biology medicine.anatomical_structure Tissue engineering medicine Articular cartilage repair 0210 nano-technology business Process (anatomy) Biomedical engineering |
| Zdroj: | Osteochondral Tissue Engineering ISBN: 9783319767109 |
| DOI: | 10.1007/978-3-319-76711-6_2 |
| Popis: | The objective of an articular cartilage repair treatment is to repair the affected surface of an articular joint’s hyaline cartilage. Currently, both biological and tissue engineering research is concerned with discovering the clues needed to stimulate cells to regenerate tissues and organs totally or partially. The latest findings on nanotechnology advances along with the processability of synthetic biomaterials have succeeded in creating a new range of materials to develop into the desired biological responses to the cellular level. 3D printing has a great ability to establish functional tissues or organs to cure or replace abnormal and necrotic tissue, providing a promising solution for serious tissue/organ failure. The 4D print process has the potential to continually revolutionize the current tissue and organ manufacturing platforms. A new active research area is the development of intelligent materials with high biocompatibility to suit 4D printing technology. As various researchers and tissue engineers have demonstrated, the role of growth factors in tissue engineering for repairing osteochondral and cartilage defects is a very important one. Following animal testing, cell-assisted and growth-factor scaffolds produced much better results, while growth-free scaffolds showed a much lower rate of healing. |
| Databáze: | OpenAIRE |
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