| Popis: |
One of the reasons for reduced male fertility is urogenital infections. In the urogenital tract of men and women, there are numerous microorganisms. Persisting for a long time in the urogenital tract, they may not cause any clinical manifestations, but cause sluggish inflammation that tends to spread and develop not only urethritis, prostatitis, epididymitis, orchitis, as well as a violation of the process of spermatogenesis. Мicroorganisms damaging the spermatogenic epithelium cause disruption of spermatogenesis and the appearance of abnormal and patholog�ical forms of sperm. The study included 122 patients diagnosed with a non-obstructive (NOA) form of azoospermia and 68 diagnosed patients with obstructive azoospermia (OA). Patients with a mixed form of azoospermia were not included in the study. The number of men with a history of Trichomonas infection in NOA was 1.6%, and in OA 1.5%. The frequency of detection of chlamydia by PCR in NOA was 3.3%, and in OA -2.9%. Mycoplasma in NOA was detected in 5.7%, and in OA in 2.9%. Ureaplasma was diagnosed in 12.3% in NOA and in 11.7% in OA. In NOA, gonorrhea was detected in 6.6%, and in OA in 13.2%. Herpes simplex virus type 2 was observed in 5.7% of men with NOA and in 7.3% of men with OA. Gardnerella was diagnosed in 9.0% of men with NOA and 13.3% of men with OA. The frequency of enterococci in men with azoospermia in OA is 32.3%, almost twice higher than in the PLA (17.2%). Infection of ejaculate/prostate secretion with Escherichia coli in NOA was detected in 13.1% of patients, and in OA in 23.5%. Staphylococcus aureus was detected only in patients with OA (4.4%). β-hemolytic streptococcus was detected in both NOA (7.4%) and OA (13.2%). Epidermal streptococcus is found in men only in OA 4.4%. The results obtained indicate that infections of the male urogenital tract and infection of seminal fluid or prostate juice are important factors, causing the development of NOA and OA. |
