Role of extracellular matrix metalloproteinases in cardiac remodelling
Autor: | Deepak Mandi, Venugopala S. Bheemanathini, Suresh C. Tyagi, Donald J. Voelker, Hanumanth K. Reddy |
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Rok vydání: | 1996 |
Předmět: |
medicine.medical_specialty
business.industry Cardiomyopathy Inflammation Dilated cardiomyopathy Tissue inhibitor of metalloproteinase Matrix metalloproteinase medicine.disease Extracellular matrix Heart failure Internal medicine cardiovascular system medicine Cardiology cardiovascular diseases Myocardial infarction medicine.symptom Cardiology and Cardiovascular Medicine business |
Zdroj: | Heart Failure Reviews. 1:73-80 |
ISSN: | 1573-7322 1382-4147 |
DOI: | 10.1007/bf00128558 |
Popis: | The latent collagenolytic system is an intrinsic part of normal myocardium. Controlled activation of this system becomes necessary in ventricular chamber remodeling following inflammation and injury, such as dilated cardiomyopathy and myocardial infarction. Evidence exists to indicate activation of collagenolytic enzymes in patients with congestive heart failure and dilated, dysfunctional ventricles due to cardiomyopathy and ischemic heart disease. |
Databáze: | OpenAIRE |
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