Role of extracellular matrix metalloproteinases in cardiac remodelling

Autor: Deepak Mandi, Venugopala S. Bheemanathini, Suresh C. Tyagi, Donald J. Voelker, Hanumanth K. Reddy
Rok vydání: 1996
Předmět:
Zdroj: Heart Failure Reviews. 1:73-80
ISSN: 1573-7322
1382-4147
DOI: 10.1007/bf00128558
Popis: The latent collagenolytic system is an intrinsic part of normal myocardium. Controlled activation of this system becomes necessary in ventricular chamber remodeling following inflammation and injury, such as dilated cardiomyopathy and myocardial infarction. Evidence exists to indicate activation of collagenolytic enzymes in patients with congestive heart failure and dilated, dysfunctional ventricles due to cardiomyopathy and ischemic heart disease.
Databáze: OpenAIRE