THE RETARDING INFLUENCES OF ADRENALECTOMY AND AGE ON ESTRADIOL-INDUCED CONNECTIVE TISSUE HYPERPLASIA IN SEMINAL VESICLES1

Autor: J.C. Allen, Evelyn Howard
Rok vydání: 1957
Předmět:
Zdroj: Endocrinology. 60:785-796
ISSN: 1945-7170
0013-7227
DOI: 10.1210/endo-60-6-785
Popis: ESTROGENS are known to stimulate hyperplasia of the fibro-muscular walls of certain portions of the male reproductive tract. In young castrated rats treated with estrogen, hyperplasia of fibro-muscular tissue in the seminal vesicles has been described by Freud (1), and comparable changes in mice seminal vesicles were noted by de Jongh (2). Korenchevsky and Dennison (3) described the histological effects of estrogen in more detail, and emphasized specifically the increase in the fibrous tissue of the submucosa in the seminal vesicles of castrated rats. In young estrogenized monkeys, Van Wagenen (4) found the most striking size increase to occur in the seminal vesicles, the increase in weight consisting of a fibro-muscular hyperplasia. However, Lacassagne (5) noted atrophic seminal vesicles in estrogenized mice in the presence of marked epidermoid hyperplasia of the coagulating gland, so that the factors influencing the action of estrogens on the fibrous tissue of the seminal vesicles do not seem to be comp...
Databáze: OpenAIRE