A novel tandem ene/Prins cyclization for the synthesis of octahydropyrano[2,3-c]pyrrole derivatives

Autor:	B. V. Subba Reddy, G. Madhusudhan Reddy, J. S. Yadav, S. Rehana Anjum
Rok vydání:	2012
Předmět:	chemistry.chemical_classification Olefin fiber Tandem Chemistry Organic Chemistry chemistry.chemical_element Prins reaction Biochemistry Aldehyde Pyrrole derivatives Drug Discovery Organic chemistry Scandium Trifluoromethanesulfonate Ene reaction
Zdroj:	Tetrahedron Letters. 53:1790-1793
ISSN:	0040-4039
Popis:	A tandem ene/Prins cyclization of olefin tethered aldehyde with an aldehyde has been accomplished using 5 mol % scandium triflate at ambient temperature to afford a novel series of cis-fused octahydropyrano[2,3-c]pyrrole derivatives in good yields with high selectivity. This is the first report on a tandem cyclization of 4-methyl-N-(3-methylbut-2-enyl)-N-(2-oxoethyl)benzenesulfonamide with aldehydes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::be0e1fa66608324ac79965b6ddf8f1bc https://doi.org/10.1016/j.tetlet.2012.01.117 Zobrazit plný text záznamu Full Text from ScienceDirect