Guz Küttnera (chronic sclerosing sialadenitis) – rzadka przyczyna powiększenia ślinianki podżuchwowej
| Autor: | Jarosław Markowski, Jacek Pająk, Małgorzata Witkowska, Lucyna Klimczak-Gołąb, Monika Świderek, Ewa Zielińska-Pająk, Katarzyna Smółka, Jarosław Paluch, Tatiana Gierek |
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| Rok vydání: | 2011 |
| Předmět: |
Pathology
medicine.medical_specialty Cirrhosis business.industry Chronic sclerosing sialadenitis medicine.disease Malignancy Submandibular gland Surgical pathology medicine.anatomical_structure stomatognathic system Otorhinolaryngology Lymphoplasmacytic Infiltrate Carcinoma Medicine Differential diagnosis business |
| Zdroj: | Otolaryngologia Polska. 65:289-292 |
| ISSN: | 0030-6657 |
| Popis: | Summary Kuttner's tumor is a benign tumour-like lesion of the salivary glands. Predominantly affects the submandibular gland. It is also known as chronic sclerosing sialoadenitis or cirrhosis of submandibular gland. This is an underrecognized entity in the surgical pathology and cytology literature. Most patients experience recurrent pain, discharge and swelling that is often associated with eating, but others only have asymptomatic hard swelling of the submandibular gland. Histologic examination of the excised submandibular glands revealed preserved lobular architecture, thickening of interlobular septa by sclerotic tissue, dense lymphoplasmacytic infiltrate, preservation of ducts with periductal fibrosis, and variable loss of acini. The morphologic appearance, in conjunction with the elevated IgG4 expression, distinguishes chronic sclerosing sialadenitis from other inflammatory diseases of the salivary glands. Chronic sclerosing sialadenitis belongs to the spectrum of IgG4-related diseases. We present a case of Kuttner's tumor in a 62-year-old female treated by surgery. Although this disease was first described by Kuttner in 1896, this clinical entity which masquerades as carcinoma is underdiagnosed by many surgeons. There is not enough evidence to support any diagnostic means that could help in the differential diagnosis of this benign condition. Given the high rate of malignancy in firm, painless lesions of the submandibular gland, surgical excision is often advocated and Kuttner's tumor is usually diagnosed by the histopathologist. |
| Databáze: | OpenAIRE |
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