Molekularna diagnostyka COVID-19 - dotychczasowe doświadczenia
| Autor: | Aleksandra A Zasada, K. Szymański, Agnieszka Trzcińska, Katarzyna Zacharczuk, Tomasz Wołkowicz, Natalia Wolaniuk, Arleta Krzysztoszek, Ewa Mosiej, Ewelina Hallmann, Kamila Formińska, Magdalena Nowakowska, Karol Wdowiak, Beata Gad, Adam Slonski, Agnieszka Kolakowska-Kulesza, Aleksandra Sadlocha, Katarzyna Pancer |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19) biology business.industry Virus transmission Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Molecular Diagnostic Method RNA virus General Medicine biology.organism_classification Rapid detection Virus Pandemic Medicine business Intensive care medicine |
| Zdroj: | Postępy Biochemii. |
| ISSN: | 0032-5422 |
| Popis: | Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2), a new highly emerging and pathogenic for human RNA virus, is responsible for the present COVID-19 pandemic. Molecular diagnostic methods, including real-time reverse transcription-PCR (RT-PCR) assay are the recommended methods for the identification and laboratory confirmation of COVID-19 cases. RT-PCR allows for detection the RNA of the virus in clinical specimens from patients suspected of COVID-19 with high specificity and sensitivity. Testing is still crucial for rapid detection of infected persons, implementation of appropriate measures to suppress further virus transmission and mitigate its impact. In response to demand of a molecular diagnostic test for SARS-CoV-2, within a first few months ongoing pandemic many commercial kits has become available on the market. However, these tests have varied in number and type of molecular targets, time of reaction as well as quality. In this study we compared different commercial tests for the detection of SARS-CoV-2 in clinical samples sending to Laboratory of Department of Virology, NIPH-NIH. |
| Databáze: | OpenAIRE |
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