Isolation of allantoin and adenosine from the marine sponge Tethya aurantia

Autor:	Frederick A. Fuhrman, Harry S. Mosher, James F. Weber, Geraldine J. Fuhrman
Rok vydání:	1981
Předmět:	Chronotropic Physiology General Medicine Marine invertebrates Biology Isolation (microbiology) biology.organism_classification Biochemistry Adenosine chemistry.chemical_compound Sponge Allantoin chemistry medicine Bioassay Purine metabolism Molecular Biology medicine.drug
Zdroj:	Comparative Biochemistry and Physiology Part B: Comparative Biochemistry. 70:799-801
ISSN:	0305-0491
DOI:	10.1016/0305-0491(81)90021-3
Popis:	1. 1. Propanol extracts of the sponge Tethya aurantia (Demospongiae) were fractionated, guided by bioassay, for a component with negative chronotropic and inotropic activity on isolated guinea pig atria. 2. 2. The bioactive component was found to be adenosine. These extracts also contained allantoin. 3. 3. This intermediate in the sequence of degradation of purines was unexpected, since it has been reported only once before to occur in marine invertebrate animals.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bdf60a0d32b9dabc8622650b2e919e40 https://doi.org/10.1016/0305-0491(81)90021-3 Zobrazit plný text záznamu