ChemInform Abstract: Synthesis and Biological Evaluation of a Bicyclo(7.4.1)enediyne

Autor: A. Bain, Wyle Solomon, Nada Zein, Gary A. Sulikowski, Shyi-Long Lee
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 27
ISSN: 0931-7597
DOI: 10.1002/chin.199642092
Popis: The synthesis of bicyclo[7.4.1]enediynes 2a and 2b are described. The bicyclo[7.4.1]enediyne 2b was found to be a poor DNA cleaver but did cause damage to several protein isolates.
Databáze: OpenAIRE